As quantum computing matures, access to scalable quantum software is increasingly critical. Today’s nascent quantum software industry is grappling with open questions that span the full stack, from how to support high-level applications programmers to how to maintain stable interfaces for hardware that is continuously growing and evolving. This talk will survey the current state of quantum software and highlight key challenges facing both the humans who write it and the hardware that executes it. I will also share our efforts to overcome these challenges so future developers can use quantum computing for important applications.