Mathieu obtained his PhD in nano-optics and nanotechnology in France in 2008 at Université de Technologie de Troyes, then worked as a post-doctoral researcher in Spain (ICFO), Australia (Macquarie University), and Austria (IQOQI) on various topics such as optical trapping, quantum optics, and superconducting circuits. In 2020, he joined the Département de Physique and Institut quantique at Université de Sherbrooke (Canada), where he now studies hybrid quantum systems with an emphasis on magneto-mechanical systems that couple mechanical and microwave components via magnetic interactions. Leveraging quantum circuits, his current work focuses on controlling and preparing quantum states in mechanical resonators for sensing and transduction applications. In early 2025, he co-founded a company, SilQ Connect, to develop quantum interconnects.